Liver transplantation
Main research interests
Organ allocation in liver transplantation (UC)
Induction immunosuppression in liver transplant candidates (UC)
Machine perfusion preservation in liver transplantation (UC, EG)
Paediatric liver transplantation, split liver, auxiliary and domino liver transplantation (UC, EG)
Transplant benefit (UC, AV)
Downstaging treatment for cancer in liver transplant candidates (UC, EG, AV,GZ)
Acute alcoholic hepatitis as indication for liver transplantation (PB)
HBV or HCV as indication for liver transplantation and prevention/treatment of recurrence after transplantation (PB and FPR)
Liver cancers as indication for liver transplantation and post-transplant follow-up (UC, PB, EG, AV)
Metabolic Liver disease as indication for liver transplantation and de novo metabolic syndrome after transplantation (PB, FPR)
Adherence to medical treatments of transplant recipients (PB)
Quality of life of transplant recipients (PB)
Coagulopathy and platelet function in liver transplant candidates and recipients (AZ, FPR, PB)
Publications
- Cillo U, Vitale A, Volk ML, Frigo AC, Feltracco P, Cattelan A, Brancaccio G, Feltrin G, Angeli P, Burra P, Lonardi S, Trapani S, Cardillo M. Liver Transplantation for T2 Hepatocellular Carcinoma during the COVID-19 Pandemic: A Novel Model Balancing Individual Benefit against Healthcare Resources. Cancers (Basel). 2021 Mar 19;13(6):1416. doi: 10.3390/cancers13061416. PMID: 33808790; PMCID: PMC8003429.
- Gringeri E, Gambato M, Sapisochin G, Ivanics T, Lynch EN, Mescoli C, Burra P, Cillo U, Russo FP. Cholangiocarcinoma as an Indication for Liver Transplantation in the Era of Transplant Oncology. J Clin Med. 2020 May 5;9(5):1353. doi: 10.3390/jcm9051353. PMID: 32380750; PMCID: PMC7290472.
- Lanari J, Hagness M, Sartori A, Rosso E, Gringeri E, Dueland S, Cillo U, Line PD. Liver transplantation versus liver resection for colorectal liver metastasis: a survival benefit analysis in patients stratified according to tumor burden score. Transpl Int. 2021 Sep;34(9):1722-1732. doi: 10.1111/tri.13981. PMID: 34448271.
- Vitale A, Scolari F, Bertacco A, Gringeri E, D'Amico F, Bassi D, D'Amico FE, Angeli P, Burra P, Lai Q, Cillo U. Sustained Complete Response after Biological Downstaging in Patients with Hepatocellular Carcinoma: XXL-Like Prioritization for Liver Transplantation or "Wait and See" Strategy? Cancers (Basel). 2021 May 17;13(10):2406. doi: 10.3390/cancers13102406. PMID: 34067521; PMCID: PMC8156031.
- Burra P, Samuel D, Sundaram V, Duvoux C, Petrowsky H, Terrault N, Jalan R. Limitations of current liver donor allocation systems and the impact of newer indications for liver transplantation. J Hepatol. 2021 Jul;75 Suppl 1:S178-S190. doi: 10.1016/j.jhep.2021.01.007. PMID: 34039488.
- Burra P, Russo FP. Sars-Cov-2 vaccination in liver transplant recipients: The 'holy grail' in a hostile environment. Liver Int. 2022 Jun;42(6):1225-1228. doi: 10.1111/liv.15226. PMID: 35678039; PMCID: PMC9347769.
- Germani G, Angrisani D, Addolorato G, Merli M, Mazzarelli C, Tarli C, Lattanzi B, Panariello A, Prandoni P, Craxì L, Forza G, Feltrin A, Ronzan A, Feltracco P, Grieco A, Agnes S, Gasbarrini A, Rossi M, De Carlis L, Francesco D, Cillo U, Belli LS, Burra P. Liver transplantation for severe alcoholic hepatitis: A multicenter Italian study. Am J Transplant. 2022 Apr;22(4):1191-1200. doi: 10.1111/ajt.16936. Epub 2022 Jan 8. PMID: 34954874.
- Russo FP, Viganò M, Stock P, Ferrarese A, Pugliese N, Burra P, Aghemo A. HBV-positive and HIV-positive organs in transplantation: A clinical guide for the hepatologist..J Hepatol. 2022 Aug;77(2):503-515
- Zanetto A, Shalaby S, Gambato M, Germani G, Senzolo M, Bizzaro D, Russo FP, Burra P. New Indications for Liver Transplantation..J Clin Med. 2021 Aug 28;10(17):3867
Funding:
Ordinary department funding.
People involved:
Umberto Cillo (Full Professor)
Patrizia Burra (Full Professor)
Francesco Enrico D’Amico (Associate Professor)
Enrico Gringeri (Associate Professor)
Francesco Paolo Russo (Associate Professor)
Alessandro Vitale (Associate Professor)
Giacomo Zanus (Full Professor)
Jacopo Lanari (Assistant Professor)
Alberto Zanetto (Assistant Professor)
Group members:
Domenico Bassi, Alessandra Bertacco, Riccardo Boetto, Silvia Caregari, Francesco D’Amico Sr, Annalisa Dolcet, Giancarlo Gemo, Marina Polacco (Consultatnt Hepatobiliary Surgeons), Martina Gambato, Giacomo Germani and Marco Senzolo (Consultant Hepatologists), Sarah Shalaby (Consultant Hepatologict and PhD student), Sara Battistella, Francesca D’Arcangelo, Marco Grasso, Lara Biribin, Marco Bucci, Giorgia Corrà, Elisa Catanzato, Elisa Zanatta (GI fellows), Paola Zanaga (Study Coordinator).